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How to grow a human : adventures in how we are made and who we are
2019
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Two summers ago, scientists removed a tiny piece of flesh from Philip Ball's arm and turned it into a rudimentary 'mini-brain.' The skin cells, removed from his body, did not die but were instead transformed into nerve cells that independently arranged themselves into a dense network and communicated with each other, exchanging the raw signals of thought. This was life'but whose? 

In his most mind-bending book yet, Ball makes that disconcerting question the focus of a tour through what scientists can now do in cell biology and tissue culture. He shows how these technologies could lead to tailor-made replacement organs for when ours fail, to new medical advances for repairing damage and assisting conception, and to new ways of 'growing a human.' For example, it might prove possible to turn skin cells not into neurons but into eggs and sperm, or even to turn oneself into the constituent cells of embryos. Such methods would also create new options for gene editing, with all the attendant moral dilemmas. Ball argues that such advances can therefore never be about 'just the science," because they come already surrounded by a host of social narratives, preconceptions, and prejudices. But beyond even that, these developments raise questions about identity and self, birth and death, and force us to ask how mutable the human body really is'and what forms it might take in years to come. 
 
- (Chicago Distribution Center)

Two summers ago, scientists removed a tiny piece of flesh from Philip Ball’s arm and turned it into a rudimentary “mini-brain.” The skin cells, removed from his body, did not die but were instead transformed into nerve cells that independently arranged themselves into a dense network and communicated with each other, exchanging the raw signals of thought. This was life—but whose? 

In his most mind-bending book yet, Ball makes that disconcerting question the focus of a tour through what scientists can now do in cell biology and tissue culture. He shows how these technologies could lead to tailor-made replacement organs for when ours fail, to new medical advances for repairing damage and assisting conception, and to new ways of “growing a human.” For example, it might prove possible to turn skin cells not into neurons but into eggs and sperm, or even to turn oneself into the constituent cells of embryos. Such methods would also create new options for gene editing, with all the attendant moral dilemmas. Ball argues that such advances can therefore never be about “just the science,” because they come already surrounded by a host of social narratives, preconceptions, and prejudices. But beyond even that, these developments raise questions about identity and self, birth and death, and force us to ask how mutable the human body really is—and what forms it might take in years to come. 
 
- (Chicago Distribution Center)

Author Biography

Philip Ball is a writer, author, and broadcaster, and he was formerly an editor at Nature. His writing on scientific subjects has appeared in places ranging from New Scientist to the New York Times. He is the author of several books, including, most recently, Beyond Weird, also published by the University of Chicago Press. He lives in London.
 
- (Chicago Distribution Center)

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Table of Contents

Prologue vii
Introduction: My Brain in a Dish 1(9)
Chapter 1 Pieces of Life
10(35)
Cells past and present
Chapter 2 Body Building
45(56)
Growing humans the old-fashioned way
First Interlude: The Human Superorganism
86(15)
How cells became communities
Chapter 3 Immortal Flesh
101(42)
How tissues were grown outside the body
Second Interlude
127(16)
Heroes and Villains: Cancer, immunity and our cellular ecosystem
Chapter 4 Twists of Fate How to reprogramme a cell
143(41)
Chapter 5 The Spare Parts Factory Making tissues and organs from reprogrammed cells
184(25)
Chapter 6 Flesh of My Flesh Questioning the future of sex and reproduction
209(38)
Chapter 7 Hideous Progeny? The futures of growing humans
247(69)
Third Interlude: Philosophy of the Lonely Mind
299(17)
Can a brain exist in a dish?
Chapter 8 Return of the Meatware
316(15)
Coming to terms with our fleshy selves
Acknowledgements 331(2)
Endnotes 333(8)
Bibliography 341(14)
Picture Credits 355(2)
Index 357

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